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Insomnia-sleep disorder, which in life probably faced almost every person. To treat inmsomnia buy ambien online. This concept includes lack of sleep, inability or inability to fully sleep, problems with falling asleep, short sleep time or constant early awakening with the inability to sleep again.

The causes of insomnia can be a great many, because the ability to sleep is influenced by both external and internal factors and you can use ambien online. Among the external causes of insomnia-the unfavorable situation around a person trying to sleep. Everything can interfere: an unfamiliar place, uncomfortable bed (too soft or, on the contrary, too hard), noise, movement around, too high or low temperature in the room. Very affect sleep stressful situations with which a person is constantly faced at home and at work. Interfere with sleep and illness, accompanied by severe pain, frequent urge to the toilet, difficulty breathing buy generic ambien online, itching skin and so on. Anxiety, fear and depression can also cause insomnia.

Insomnia can have both chronic, permanent character, and to happen very seldom, several times a year. If you usually do not bother with sleep problems, but at some point you can not sleep because of stress, you can try to solve the problem yourself. But if insomnia is delayed for a long period or its episodes are often repeated, if insomnia is caused by depression or fears, a person needs a doctor's consultation.

A person can try to solve their own problems with falling asleep. First, make sure you are leading the right lifestyle. Sometimes this causes insomnia, and it may take several weeks to return the regime to its natural course.

What you should not do clearly – is to drink alcohol cheap ambien rx online in the evenings. Of course, you may think that alcohol has a calming effect and helps to sleep. But this myth is associated with the sedative effect of alcohol on the body: a person falls asleep for a short time, then wakes up and can not sleep anymore ambien for sale online. This is due to the effect of alcohol on the deep sleep phase. Stimulating, invigorating effect has nicotine buy ambien online, so to restore a healthy sleep you have to give up cigarettes.

It's no secret that caffeine is one of the best invigorating remedies. It remains in the human body for the whole day. Therefore, if you have a suspicion that it prevents coffee to fall asleep at night, give it up and caffeine-containing products buy zolpidem online overnight (Cola, chocolate, tea).

Sleep can also be affected by medications you take. For example, some anti-food products sold in pharmacies without a special prescription have the same effect on the body as coffee. Therefore, if you have problems with falling asleep, be sure to ask the pharmacist how this medicine will affect your sleep.

Overeating at night can also prevent you from falling asleep, because an unpleasant feeling in the stomach will bother you at night buy ambien online no prescription. To satisfy your hunger, limit yourself to a light snack: crackers with honey and milk, mint or other herbal tea and so on.

Bath procedures should be carried out a couple ambien no rx of hours before bedtime. The muscles will relax and you will want to sleep quickly. But immediately before going to bed it is better to refrain from swimming, because hot water will affect your body as a stimulant cheap ambien otc, giving vigor and energy.

During the day, it is useful to do physical exercises, because physical activity will relieve tension, give energy in the morning and improve the process of falling asleep. But just before going to bed do not do exercises, because it stimulates the nervous system and disrupt sleep ambien discount.

Prepare a place to sleep: it should be as dark and quiet. If you sleep interfere with noisy neighbors-buy earplugs. However, some people fall asleep much better to quiet music. The bed should not be too hard or too soft. It is optimal to buy a dense comfortable orthopedic mattress.

Give up a long sleep after noon, because it only contributes to insomnia buy ambien online legally.

Before going to bed, it is useful to read a little – it relaxes and causes slumber. But the usual attempts to count sheep is not the best way to fall asleep order ambien online: you will only focus on a certain task and will not be able to fully relax. Better dream, imagine yourself in some nice place – in the forest, on the beach or in the mountains.

Before going to bed, try to abstract as much as possible from everyday thoughts, cost calculation, thinking about work plans or memories of unpleasant moments. It will cause stress and bother you by disturbing your sleep.

In chronic insomnia, the doctor may recommend you medication, but sleeping pills should be taken only in extreme cases. Sleeping pills usually do not cure insomnia, but only oppress the mind of man, and their long-term use can cause addiction. If insomnia is caused by any nervous disorder or other disease – the doctor will choose the appropriate therapy.

Zolpidem is a hypnotic belonging to the group of imidazopiridins, and is a selective agonist of the subclass of omega - 1-benzodiazepine receptors. Has sedative action, while when used in normal doses does not have anxiolytic, anticonvulsant and Central muscle relaxant actions. Benzodiazepinove stimulates receptors (omega) in the alpha-subunit of GABA-receptor complexes localized in the region IV plates sensory-motor areas of the cortex, reticular departments black substance, visual hillocks ventral thalamic complex, bridge, pale globe and other Interaction with omega - receptors cheap ambien online leads to the discovery of neuronal Informix channels for ions chlorine order ambien online.

Shortens sleep time, reduces the number of night awakenings, increases the overall duration of sleep and improves its quality. Extends phase II of sleep and the deeper stages of sleep (III and IV). Does not cause drowsiness during the day.

Pharmacokinetics

Zolpidem is rapidly absorbed from the gastrointestinal tract. The time to reach the maximum concentration in plasma (TCmax)after oral administration is 0.5-3 h. Bioavailability-70%, plasma protein - 92%. There is a linear relationship between the dose and plasma concentrations. It is metabolized in the liver to form three inactive metabolites, which are excreted by the kidneys (56%) and through the intestine (37%). The average half-life (T1/2) of 2.4 h. the Volume of distribution of 0.5 ± 0.02 l/kg does Not induce liver enzymes. Persons elderly clearance in plasma can be reduced without a significant increasing T1/2 (on average 3 hours), while Cmax increased by 50%. Patients with acute violations of the kidney klirens increasing slightly. Patients with human liver bioavailability increasing, T1/2 increases up to 10 h Stands out in small quantities in breast milk.

Indications

Sleep disorders: difficulty in falling asleep, early and night awakenings.

Contraindications

Hypersensitivity to zolpidem or other component of the drug, acute and/or severe respiratory failure, severe acute or chronic hepatic insufficiency, sleep apnea (including in advance), children's age (till 18 years); pregnancy, lactation.

Due to the presence of lactose in the composition: hereditary lactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome ambien otc.

Method of application and doses

Inside (just before bed) in a single dose of 10 mg.

In elderly or debilitated patients buy ambien online legally, with abnormal liver function, treatment is initiated with doses of 5 mg. If necessary (lack of clinical effect) and good tolerability the dose may be increased to 10 mg a Maximum daily dose of 10 mg. the treatment Course should not exceed 4 weeks. With transient insomnia, the recommended course of treatment is 2-5 days, with situational - 2-3 weeks.

Very short periods of treatment do not require the gradual withdrawal of the drug. In the case of long-term use of the drug to reduce the possibility of insomnia cancellation zolpidema should be carried out gradually (first, reducing the daily dose and then the abolition of the drug buy ambien online overnight).

Side effects

Zolpidem is usually well tolerated.

The frequency of adverse reactions: very often-more than 10% cheap ambien cr online sale, often - more than 1% and less than 10%, infrequently - more than 0.1% and less than 1%), rarely - more than 0.01% and less than 0.1%, very rarely - less than 0.01% (including individual cases ambien without prescription), the frequency is unknown (based on available data, the frequency of occurrence is impossible).

From the nervous system: often-drowsiness, feeling of intoxication, headache, dizziness, increased insomnia, anterograde amnesia buy ambien online safe (the effects of amnesia may be associated with behavioral reactions), the risk of which increases in proportion to the dose, hallucinations, excitation, nightmares; infrequently-confusion, irritability; the frequency is unknown - impaired consciousness, dysphoria, aggression, visual and auditory hallucinations, irritability, behavioral responses, somnambulism, drug dependency (can develop even when using therapeutic doses), with drug discontinuation - syndrome cancel or rebound insomnia, decreased libido, impaired gait, ataxia, falls (mainly in patients elderly), drug addiction (decrease sedative and hypnotic action when applying for weeks). Most of the side effects from the psyche are paradoxical reactions buy ambien online pharmacy.

From the digestive system: often-diarrhea, nausea, vomiting, abdominal pain; the frequency is unknown - increased activity of liver enzymes buy ambien online cheap.

On the part of the musculoskeletal system: the frequency is unknown-muscle weakness.

On the part of the skin: the frequency is unknown-rash, itching, urticaria, hyperhidrosis.

Allergic reactions: the frequency is unknown-angioedema.

Other: often - fatigue; rare - diplopia.

Overdose of ambien without prescription

Symptoms: impaired consciousness (from confusion and inhibition to coma), ataxia, low blood pressure, respiratory depression.

Treatment with ambien prescription: induction of vomiting within 1 h after overdose, activated charcoal, if after the overdose has been more than 1 h (with preserved consciousness inside buy ambien online over the counter, at the unconscious through a tube), washing stomach, symptomatic therapy. As an antidote, flumazenil is recommended (an antagonist of benzodiazepine receptors), but it should be remembered that antagonism with benzodiazepine receptors can lead to the development of seizures, especially in patients with epilepsy. Dialysis is ineffective buy ambien online without prescription.

Special instruction

The persistence of insomnia for 7-14 days of treatment indicates the presence of primary mental disorders and/or disorders of the nervous system. Therefore, in order to identify these disorders, it is necessary to regularly reassess the patient's buy ambien online otc condition.

To reduce the risk of developing anterograde amnesia, patients should have conditions for continuous 7-8-hour sleep.

If application buy zolpidem online may experience mental and behavioural (including paradoxical) reactions (risk of higher in elderly patients).

If such reactions occur, the intake of zolpidem should be stopped.

After a course of admission for a few weeks may be some reduction in sedative and hypnotic effects of zolpidem.

The use of zolpidem (especially long) can lead to the formation of physical and/or mental dependence, the risk of which increases with increasing dose and duration of treatment, as well as in patients with otc amnien online a history of alcohol abuse or other drugs and non-drugs. Such patients during treatment should be under close supervision. However, dependence (extremely rare) may also occur in therapeutic doses and/or in patients without individual risk factors.

The combination of cheap zolpidem online with benzodiazepines increases the risk of drug dependence.

In elderly patients or with impaired liver function may significantly increase T1/2 zolpidem, which may lead to the accumulation of the drug when it is re-taken. Based on the features of the pharmacokinetics of zolpidem, with CPN cumulation of the drug is not expected.

When using zolpidem in elderly people should be careful, due to the risk of severe sedative and/or muscle relaxant effects buy ambien otc.

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